Nature Made. Rx Essentials™ Daily Supplement — Tailored to Your Prescription

Taking prescription medications for arthritis

Through extensive research, Nature Made science experts have identified essential nutrients helpful when taking non-steroidal anti-inflammatory drugs (NSAIDs) for arthritis, such as Ibuprophen, Naproxen, or Aspirin.

Folic Acid

Some experts believe that elevated levels of homocysteine, may affect heart health, so supplementing with Folic Acid, also known as folate, to reduce homocysteine levels may be important to maintaining a healthy heart.1 Lowering homocysteine levels has also been linked to healthy bones and cognitive function.

A special health report about pain from Harvard Medical School states, “Supplement-drug interactions. NSAIDs may interfere with folate (folic acid) absorption, so you may want to increase your intake of dietary folate or take a folic acid supplement if you’re using an NSAID regularly.”2


Vitamin C

Vitamin C, or ascorbic acid, provides a range of important benefits, including forming collagen, and helping maintain cartilage, bones, and teeth. It’s also an antioxidant, which helps protect the body from damage by free radicals that may impact the aging process.

Studies show that people taking anti-inflammatory medications to treat arthritis may benefit from taking vitamin C, which is essential to maintaining healthy cartilage and joints.3


Vitamin D

Vitamin D enhances calcium absorption and calcium is well documented as being essential to the strength of bones and teeth.

People with osteoarthritis may have lower blood levels of vitamin D.4 Vitamin D is an essential nutrient for healthy muscles and optimal bone health.


1Quinlivan EP, et al Importance of both folic acid and vitamin B12 in reduction of risk of vascular disease. Lancet. 2002 Jan 19;359(9302):227-8

2What to do About Pain Special Health Report from Harvard Medical School. Harvard Health Publications, P.O. Box 9306, Big Sandy, TX 75755-9306 or online at www.health.harvard.edu/

3Felson DT et al. Osteoarthritis: New insights. Part 1: The disease and its risk factors. Annals of Internal Medicine. October 17, 2000. 133:8: 635-646

McAlindon TE, et al: Do antioxidant micronutrients protect against the development and progression of knee osteoarthritis? Arthritis Rheum. 1996 Apr;39(4):648-56.

4McAlindon T, Felson D. Nutrition: risk factors for osteoarthritis. Ann Rheum Dis 1997;56:397-402